Ever talk about your friend's cat and find yourself saying "It's so cute! I mean...he's so cute. Or she? I don't know, but it's cute." Well, we've got a little tip for you: If the cat has two colors, go with "she."
In The Genes
The Exception To The Rule
Why Calico Cats Are Almost Always Female
Share the knowledge!
Key Facts In This Video
The X chromosome from a male cat's mother determines his fur color, but in females, the X chromosomes from both parents take turns determining fur color. 00:50
The tri-colored calico coloring with white happens due to a gene unrelated to the X and Y chromosomes. 02:09
A male calico cat can have tri-colored fur if he inherits an extra X chromosome, making his genetic makeup XXY. In humans, this condition is known as Klinefelter Syndrome. 02:26