There's A Powerful Painkiller In Your Spit

NEWS: The Curiosity Podcast is out! Subscribe on iTunes, Google Play Music, Stitcher, SoundCloud and add the RSS feed to any podcast player. If you love it please consider leaving us a review.

Opiorphin is a chemical in human saliva that is a natural painkiller. In one study on rats, just 1 milligram of opiorphin per kilogram of body weight achieved the same painkilling effect as 3 milligrams of morphine. It's been suggested that the molecule is also a natural antidepressant. The molecule breaks apart quickly in human intestines, however, and demonstrates poor penetration of the blood-brain barrier, which means that it would need to be modified before it could function as a painkiller in humans.

Share the knowledge!

Key Facts In This Video

  1. Before aspirin was invented, people reduced fevers and inflammation by chewing the bark of the white willow tree. 00:04

  2. TNT is poisonous, and skin exposure to it will cause your skin to turn yellow or orange. 01:11

  3. Opiorphin is a chemical in human saliva that is more potent than morphine. 02:26

If you liked this you'll love our podcast! Check it out on iTunesGoogle Play MusicStitcherSoundCloud, search 'curiosity' on your favorite podcast app or add the RSS Feed URL.