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Leaving your dog at home alone can be one of the saddest moments of your day—that is, assuming you don't later come home to see that Fido's separation anxiety has made him destroy the couch. According to the ASPCA, one way to ease mild separation anxiety in your pet is through something called counterconditioning. Counterconditioning teaches a dog to develop an association between being alone and something good, like getting a treat or a toy. Or, if fMRI brain scans are any indication, something that smells like you.