There may be variations, based on sex, in the way that both mice and humans remember pain, according to new research.
Scientists increasingly believe that one of the driving forces in chronic pain — the number one health problem in both prevalence and burden — appears to be the memory of earlier pain.
The researchers found that men (and male mice) remembered earlier painful experiences clearly. As a result, they felt stress and were hypersensitive to later pain when they returned to the location where they'd experienced it. Earlier experiences of pain didn't seem to stress women (and female mice).